JPH0225911B2 - - Google Patents

Info

Publication number
JPH0225911B2
JPH0225911B2 JP58118009A JP11800983A JPH0225911B2 JP H0225911 B2 JPH0225911 B2 JP H0225911B2 JP 58118009 A JP58118009 A JP 58118009A JP 11800983 A JP11800983 A JP 11800983A JP H0225911 B2 JPH0225911 B2 JP H0225911B2
Authority
JP
Japan
Prior art keywords
compound
oxepin
ethyl
acid
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58118009A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6028972A (ja
Inventor
Hiroshi Takizawa
Yoshimasa Ikuji
Takemori Oomori
Katsuichi Shuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP58118009A priority Critical patent/JPS6028972A/ja
Priority to US06/625,000 priority patent/US4596804A/en
Priority to CA000457545A priority patent/CA1225090A/en
Priority to EP84107410A priority patent/EP0130555A3/en
Publication of JPS6028972A publication Critical patent/JPS6028972A/ja
Publication of JPH0225911B2 publication Critical patent/JPH0225911B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP58118009A 1983-06-29 1983-06-29 ジベンゾ［ｂ，ｅ］オキセピン誘導体 Granted JPS6028972A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP58118009A JPS6028972A (ja) 1983-06-29 1983-06-29 ジベンゾ［ｂ，ｅ］オキセピン誘導体
US06/625,000 US4596804A (en) 1983-06-29 1984-06-26 Dibenz[b,e]oxepin compounds
CA000457545A CA1225090A (en) 1983-06-29 1984-06-27 Dibenz ¬b,e| oxepin derivatives
EP84107410A EP0130555A3 (en) 1983-06-29 1984-06-28 Dibenz (b,e) oxepin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58118009A JPS6028972A (ja) 1983-06-29 1983-06-29 ジベンゾ［ｂ，ｅ］オキセピン誘導体

Publications (2)

Publication Number Publication Date
JPS6028972A JPS6028972A (ja) 1985-02-14
JPH0225911B2 true JPH0225911B2 (en]) 1990-06-06

Family

ID=14725791

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58118009A Granted JPS6028972A (ja) 1983-06-29 1983-06-29 ジベンゾ［ｂ，ｅ］オキセピン誘導体

Country Status (4)

Country Link
US (1) US4596804A (en])
EP (1) EP0130555A3 (en])
JP (1) JPS6028972A (en])
CA (1) CA1225090A (en])

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02106116U (en]) * 1989-02-14 1990-08-23

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188802A3 (en) * 1984-12-26 1986-08-20 Kyowa Hakko Kogyo Co., Ltd. Dibenz (b,e) oxepin derivative and antiallergic agent
GB8520662D0 (en) * 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
US4882351A (en) * 1987-10-14 1989-11-21 Roussel Uclaf Tricyclic compounds
AU612437B2 (en) * 1987-12-14 1991-07-11 Kyowa Hakko Kogyo Co. Ltd. Tricyclic compounds
US4999363A (en) * 1988-06-09 1991-03-12 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds
US5242931A (en) * 1988-06-09 1993-09-07 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds as TXA2 antagonists
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
SE9302135D0 (sv) * 1993-06-18 1993-06-18 Kabi Pharmacia Ab New pharmaceutical composition
CA2466790A1 (en) * 2001-11-13 2003-05-22 Kyowa Hakko Kogyo Co., Ltd. Preventive or therapeutic agent for pruritus
JPWO2005011674A1 (ja) * 2003-08-05 2006-09-14 協和醗酵工業株式会社 気管支喘息の予防及び／または治療剤
EP1769794A1 (en) * 2004-07-16 2007-04-04 Kyowa Hakko Kogyo Co., Ltd. Medicament for preventing and/or treating sleep disorder
JP4993901B2 (ja) * 2005-11-29 2012-08-08 水ｉｎｇ株式会社 中空糸膜モジュール
US8222419B2 (en) 2006-09-29 2012-07-17 Nippon Zoki Pharmaceutical Co., Ltd. Oxepin derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1543346A1 (de) * 1966-04-30 1969-09-25 Boehringer Mannheim Gmbh Verfahren zur Herstellung basischer Derivate des Dibenzoxepins und Dibenzothiepins
US4011222A (en) * 1973-03-30 1977-03-08 Hoffmann-La Roche Inc. Fluoro-substituted dibenzo[b,f]thiepins
US4032525A (en) * 1974-01-04 1977-06-28 Hoffmann-La Roche Inc. Dibenz[b,f]oxepin derivatives
DE2704934A1 (de) * 1976-02-17 1977-08-18 Sandoz Ag Organische verbindungen, ihre herstellung und verwendung
US4396550A (en) * 1980-04-22 1983-08-02 Kyowa Hakko Kogyo Co., Ltd. Dibenz [b,e] oxepin derivatives
DE3175674D1 (en) * 1981-07-09 1987-01-15 Merck & Co Inc Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions
JPS58126883A (ja) * 1982-01-25 1983-07-28 Kyowa Hakko Kogyo Co Ltd ジベンゾ〔ｂ，ｅ〕オキセピン誘導体を含有してなる抗喘息剤

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02106116U (en]) * 1989-02-14 1990-08-23

Also Published As

Publication number Publication date
EP0130555A2 (en) 1985-01-09
EP0130555A3 (en) 1987-09-02
JPS6028972A (ja) 1985-02-14
CA1225090A (en) 1987-08-04
US4596804A (en) 1986-06-24

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